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Michael DiMattina M.D.

4 New Natural Cycle IVF (NCIVF) Pregnancies - Is this you?

Hello Everyone!

Yesterday was a special day for us at Dominion Fertility. Four new clinical NCIVF pregnancies were diagnosed on ultrasound in one day. So far, we are off to a very strong start this year in our NCIVF program. Please note that 3 of these 4 patients achieved their pregnancy in their first treatment of NCIVF and the fourth in her second treatment. We are now finding that 64% of our pregnancies occur with the first embryo transfer and 21% with the second embryo transfer. Please see my last post for more details regarding our stats. Our Natural Cycle IVF web site stats will be updated shortly.

So, here are their stories that I would like to share with you:

Two Patients With Diminished Ovarian Reserve:

1. T.K. is a 39 yr old military officer, with primary infertility for the past 8 years. She first came to see me on Jan 28, 2010. Her evaluation at Walter Reed medial center revealed an abnormal day 3 FSH level of 13.3 We performed NCIVF in March with embryo transfer of one embryo but she was unsuccessful with her first attempt. The very next month we again performed NCIVF and this time she naturally produced 2 ova which resulted in embryo transfer of 2 blastocysts with ultrasound confirmation of a singleton intrauterine pregnancy yesterday. Obtaining 2 ova is unusual as most natural cycles usually result in just a single egg.

2. M.M. is a 36 year old nurse practitioner with primary infertility for one year. She first came to see me on November 11, 2009. Her evaluation demonstrated decreased ovarian reserve with her serum AMH level of 0.9 (normal >2.0), and an abnormal day 3 estradiol of 87pg/ml. She was first treated with Clomid - IUI but this was unsuccessful. So, she underwent her first NCIVF and on April 8, she had a single blastocyst embryo transfer with her pregnancy confirmed yesterday on ultrasound. She has been referred back to her Obstetrician for Ob care.

Male Factor with Testicular Biopsy and NCIVF:

3. L.M. is a 30 year old financial advisor with primary infertility whose husband underwent a vasectomy in 2000. Successful testicular biopsy was performed followed by her first NCIVF treatment with embryo transfer on April 3. Yesterday, a single intrauterine pregnancy was diagnosed by ultrasound at 7 weeks gestation and she has been referred to her obstetrician.

Infertility after a Vasectomy Reversal:

4. C.C. is a 24 year old who had been infertile for one year who presented to us on December 15, 2009. Her male partner underwent a vasectomy 14 years ago with a vasectomy reversal (vasovasotomy) 10 years ago. Unfortunately, this resulted in very poor sperm quality with a low sperm count, motility and morphology. She underwent her first NCIVF treatment with embryo transfer of one blastocyst embryo on April 14. This resulted in a viable intrauterine pregnancy confirmed yesterday by ultrasonography.

We have treated many patients with all different types of infertility using NCIVF and we remain enthusiastic with our experience and results obtained. Congratulations to our most recently successful NCIVF patients! Michael DiMattina, M.D.











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Jess O'Connor Comment by Jess O'Connor on May 23, 2010 at 7:24am
I'm very happy to read that there are more couples who have successfully undergone NC-IVF this year! My husband and I were treated for male factor infertility with one round of NC-IVF in January and I am now `19 weeks pregnant. Everything is going very well and we're extremely happy. Thank you Dominion!

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John David Gordon MD replied to anonymous's discussion '2 miscarriages'
Always better to have had a near miss than nothing...the data from the CDC suggests pregnancy rates in patients undergoing IVF are higher in those with prior pregnancy loss in a previous cycle compared with those that came up totally empty…
1 hour ago
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John David Gordon MD replied to melissa wright's discussion 'a little about me'
Hi Melissa Most commonly biochemical pregnancies are genetic in origin as the embryo was normal enough to implant but not normal enough to keep growing. Any heavy bleeding that is unusual is a reason to at least check in with your doctor... Good…
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John David Gordon MD replied to Kristen's discussion 'Progesterone side effects during 2ww'
Agree that the emotional ups and downs make the 2ww the worst part of the whole process for many of our patients. Hard to understand why progesterone would cause cramping as progesterone is actually a uterine relaxant but there are always exceptions…
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John David Gordon MD replied to Anonymous's discussion 'Natural cycle IVF'
Absolutely! Especially for those who only want one child and do not want to deal with the possiblility of extra embryos in teh freezer! DrG
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Bonus baby with NC IVF after being told FSH levels precluded another IVF attempt!

Just received a wonderful email from a lovely couple who traveled all the way from Georgia to do NC IVF here at Dominion. Having had a previous IVF/ICSI baby in 2006 they had returned to their RE for another attempt at IVF. Previously the response to medications had been poor and this time the response was even worse with no retrieval even attempted. Her FSH was 18.9 and they were told that essentially no good options existed in terms of IVF. Fortunately, they had heard about NC IVF and we had…See More
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Anonymous replied to Kristen's discussion 'Progesterone side effects during 2ww'
Totally agree with you about the progesterone, I've taken the supps and had such bad PMS like symptoms that I knew it didn't work long before the blood test.  
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Progesterone side effects during 2ww

I'm currently 11dp7dt after a frozen blastocyst transfer, and I've been pretty shocked by the side effects of the progesterone & estrace.  The cramping, bloating, breast soreness, and emotional nosedive are overwhelming.  What concerns me most is the cramping.   A number of times it was bad enough to wake me from a sound sleep.  I was told that was ok and normal as long as there is no bleeding.  I am doing the progesterone suppositories.  I can't help but wonder how or why an embryo would…See More
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melissa wright replied to melissa wright's discussion 'a little about me'
Thank you for ur input dr gordon. It really means a lot 2 me 2 get advise from other doctors such as yourself. I have however had what I was told a chemical pregnacy. And I am pretty sure I had another 1 this mth. I had a x-ray done with the dye…
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