Hi Everyone!
I love to post stories such as this patient, M. R., as it just lights me and our staff up! I will also present some of our NCIVF results here too.
M.R. is now a 42 year old nurse, who got pregnant and delivered two successful pregnancies in 2006 and 2008 having two healthy girls. She then experienced secondary infertility and she also desired male gender selection. We tried some simple intrauterine inseminations(IUI), but this was unsuccessful, so M.R. decided to give NCIVF a shot. At her advanced reproductive age, decreased ovarian reserve was evident as her serum AMH level was low at 0.3 (normal >2.0).
On April 6, one egg was obtained and successfully fertilized using male enriched gender selected sperm, and 5 days later a single blastocyst embryo was transferred. Two weeks later, her sonogram revealed an early intrauterine pregnancy. This treatment was all in her normal menstrual cycle with no ovarian stimulating drugs.
Recently, we submitted for publication our 3 yr experience with NCIVF. For all patients, under 40 years old, our clinical pregnancy rates are as follows:
________Pregs/egg collection_______Pregs/embryo transfer
2007________13.3%____________________23%
2008________ 21.8%___________________43.7%
2009________ 21.6%___________________36%
Total________22.5%___________________35.3%
In January 2007, be began our NCIVF program and there was a definite learning curve. With continued experience, however, we promptly doubled our pregnancy rates in 2008. Please keep in mind that we achieved these results by transferring only one embryo and without the use of ovarian stimulation drugs. The vast majority of these patients achieved pregnancy within their first (64.3%) or second (21.4%) NCIVF embryo transfer(s)! And now we are offering NCIVF to patients who have decreased ovarian reserve or have elevations in their FSH. Such patients will, understandably, have lower success rates but some of these patients have already achieved a successful pregnancy with us using NCIVF, such as our patient presented here.
The scope of this forum does not permit a detailed presentation of data here and that is why we have sent for publication the results of our NCIVF program. We firmly believe that it is only a matter of time before NCIVF is offered as a viable treatment option by most reputable IVF programs in the United States as it is in Europe and elsewhere.
So, congrats to our patient M.R.! We hope it is a boy!!! Michael DiMattina, M.D.
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